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Stents DES

Coronary stents are small cylindrical tubes with a mesh structure used during percutaneous coronary interventions (PCI, PTCA), i.e., angioplasty (stenting). The coronary arteries, on the other hand, supply oxygen-rich blood to the heart muscle, thus ensuring its proper function. Stents are implanted in patients with narrowing of the coronary vessels, i.e., patients with myocardial infarction or stable coronary artery disease (chronic coronary syndrome) and persistent symptoms (e.g., chest pain, shortness of breath, deterioration of exercise tolerance) despite pharmacological treatment.

How coronary stenst with sirolimus work

Stents widen the lumen of the diseased coronary artery and maintain its patency, i.e., they act as a scaffold (a stent is a permanently deployed implant). Currently, classic metal stents (BMS), drug-eluting stents (DES), and bioresorbable stents are on the market. Currently, drug stents (DES) are the most implanted. They consist of a metal platform (cobalt-chrome or platinum-chrome alloy, now rarely stainless steel) and a drug-releasing polymer, such as sirolimus or everolimus. The drug has an antiproliferative effect and thus reduces the risk of re-narrowing (restenosis) at this site.

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